Please see below for all of our team's published papers relating to "Treatment." Publications marked with asterisks (**) have a specific focus on diversity, equity, and inclusion.

How Well Do Our Treatments Work in the Real World?

Datta, N., Matheson, B., Plessow, F., Citron, K., Le Grange, D., Schlegl, S., & Lock, J. (2024). The Impact of Family-Based Treatment for Adolescent Anorexia Nervosa on Compulsive Exercise Attitudes and Behaviors. The International journal of eating disorders, 10.1002/eat.24334. Advance online publication. https://doi.org/10.1002/eat.24334

Forsberg, S., Gorrell, S., Accurso, E. C., Trainor, C., Garber, A., Buckelew, S., & Le Grange, D. (2023). Family-based treatment for pediatric eating disorders: Evidence and guidance for delivering integrated interdisciplinary care. Children's health care: journal of the Association for the Care of Children's Health, 52(1), 7–22. https://doi.org/10.1080/02739615.2021.1984240

Garber, A. K., Cheng, J., Accurso, E. C., Adams, S. H., Buckelew, S. M., Kapphahn, C. J., Kreiter, A., Le Grange, D., Machen, V. I., Moscicki, A. B., Sy, A., Wilson, L., & Golden, N. H. (2021). Short-term outcomes of the study of refeeding to optimize inpatient gains for patients with anorexia nervosa: A multicenter randomized clinical trial. JAMA pediatrics, 175(1), 19–27. https://doi.org/10.1001/jamapediatrics.2020.3359

Golden, N. H., Cheng, J., Kapphahn, C. J., Buckelew, S. M., Machen, V. I., Kreiter, A., Accurso, E. C., Adams, S. H., Le Grange, D., Moscicki, A. B., Sy, A. F., Wilson, L., & Garber, A. K. (2021). Higher-calorie refeeding in anorexia nervosa: 1-Year outcomes from a randomized controlled trial. Pediatrics, 147(4), e2020037135. https://doi.org/10.1542/peds.2020-037135

Gorrell, S., Schaumberg, K., Boswell, J. F., Hormes, J. M., & Anderson, D. A. (2021). Female athlete body project intervention with professional dancers: A pilot trial. Eating disorders, 29(1), 56–73. https://doi.org/10.1080/10640266.2019.1632592

Le Grange, D., Pradel, M., Pogos, D., Yeo, M., Hughes, E. K., Tompson, A., Court, A., Crosby, R. D., & Sawyer, S. M. (2021). Family-based treatment for adolescent anorexia nervosa: Outcomes of a stepped-care model. The International journal of eating disorders, 54(11), 1989–1997. https://doi.org/10.1002/eat.23629

Matheson, B. E., Bohon, C., Le Grange, D., & Lock, J. D. (2024). Family-based treatment (FBT) for loss of control (LOC) eating in youth: Current knowledge and future directions. Eating disorders, 32(1), 1–12. https://doi.org/10.1080/10640266.2023.2229091

Reilly, E. E., Rockwell, R. E., Ramirez, A. L., Anderson, L. K., Brown, T. A., Wierenga, C. E., & Kaye, W. H. (2020). Naturalistic outcomes for a day-hospital programme in a mixed diagnostic sample of adolescents with eating disorders. European eating disorders review: the journal of the Eating Disorders Association, 28(2), 199–210. https://doi.org/10.1002/erv.2716

**Riddle, M., Blalock, D. V., Robertson, L., Duffy, A., Le Grange, D., Mehler, P. S., Rienecke, R. D., & Joiner, T. (2024). Comparing eating disorder treatment outcomes of transgender and gender diverse adolescents with those of cisgender adolescents. The International journal of eating disorders, 57(7), 1555–1565. https://doi.org/10.1002/eat.24195

Rienecke, R. D., Blalock, D. V., Duffy, A., Manwaring, J., Le Grange, D., Johnson, C., Mehler, P. S., & McClanahan, S. F. (2021). Posttraumatic stress disorder symptoms and trauma-informed care in higher levels of care for eating disorders. The International journal of eating disorders, 54(4), 627–632. https://doi.org/10.1002/eat.23455

Robison, M., Velimirovic, M., Rice, T., Duffy, A., Riddle, M., Manwaring, J., Rienecke, R. D., McClanahan, S., Blalock, D. V., Le Grange, D., Mehler, P. S., & Joiner, T. E. (2024). Are Suicide-Specific Interventions Required to Reduce Suicidal Ideation? An Empirical Examination in a Clinical Sample of Eating-Disorder Participants. Clinical Psychological Science, 0(0). https://doi.org/10.1177/21677026241274746

Clinical Trials (or Studies Comparing Treatments)

Haas, V., Wechsung, K., Kaiser, V., Schmidt, J., Raile, K., Busjahn, A., Le Grange, D., & Correll, C. U. (2024). Comparing family-based treatment with inpatient treatment in youth with anorexia nervosa eligible for hospitalization: A 12-month feasibility study. The International journal of eating disorders, 57(2), 388–399. https://doi.org/10.1002/eat.24098

Hambleton, A., Aouad, P., Miskovic-Wheatley, J., Le Grange, D., Touyz, S., & Maguire, S. (2022). The efficacy of family treatments for adolescent anorexia nervosa in specialist versus non-specialist settings: Protocol for a systematic review and meta-analysis. Journal of eating disorders, 10(1), 120. https://doi.org/10.1186/s40337-022-00645-3

Murray, S. B., Levinson, C. A., Farrell, N. R., Nagata, J. M., Compte, E. J., & Le Grange, D. (2020). The open versus blind weight conundrum: A multisite randomized controlled trial across multiple levels of patient care for anorexia nervosa. The International journal of eating disorders, 53(12), 2079–2085. https://doi.org/10.1002/eat.23397

Nadler, J., Correll, C. U., Le Grange, D., Accurso, E. C., & Haas, V. (2022). The Impact of Inpatient Multimodal Treatment or Family-Based Treatment on Six-Month Weight Outcomes in Youth with Anorexia Nervosa: A Naturalistic, Cross-Continental Comparison. Nutrients, 14(7), 1396. https://doi.org/10.3390/nu14071396

Vogel, E. N., Singh, S., & Accurso, E. C. (2021). A systematic review of cognitive behavior therapy and dialectical behavior therapy for adolescent eating disorders. Journal of Eating Disorders, 9(1), 131. https://doi.org/10.1186/s40337-021-00461-1

Who Do Our Treatments Work Best For?

Datta, N., Hagan, K., Bohon, C., Stern, M., Kim, B., Matheson, B. E., Gorrell, S., Le Grange, D., & Lock, J. D. (2023). Predictors of family-based treatment for adolescent eating disorders: Do family or diagnostic factors matter?. The International journal of eating disorders, 56(2), 384–393. https://doi.org/10.1002/eat.23867

Denning, D. M., Perry, T. R., Reilly, E. E., Berner, L. A., Velkoff, E. A., Kaye, W. H., Wierenga, C. E., & Brown, T. A. (2022). Associations of suicide risk with emotional reactivity, dysregulation, and eating disorder treatment outcomes. Suicide & life-threatening behavior, 52(6), 1126–1139. https://doi.org/10.1111/sltb.12907

Gorrell, S., Hughes, E. K., Sawyer, S. M., Roberts, S. R., Nagata, J. M., Yeo, M., Lock, J., & Le Grange, D. (2022). Gender-based clinical differences in evidence-based treatment for adolescent anorexia nervosa: analysis of aggregated randomized controlled trials. Eating and weight disorders, 27(3), 1123–1130. https://doi.org/10.1007/s40519-021-01257-7

Gorrell, S., Lebow, J., Kinasz, K., Mitchell, J. E., Goldschmidt, A. B., Le Grange, D., & Accurso, E. C. (2020). Psychotropic medication use in treatment-seeking youth with eating disorders. European eating disorders review: The journal of the Eating Disorders Association, 28(6), 739–749. https://doi.org/10.1002/erv.2788

Hagan, K. E., Matheson, B. E., Datta, N., L'Insalata, A. M., Onipede, Z. A., Gorrell, S., Mondal, S., Bohon, C. M., Le Grange, D., & Lock, J. D. (2023). Understanding outcomes in family-based treatment for adolescent anorexia nervosa: A network approach. Psychological medicine, 53(2), 396–407. https://doi.org/10.1017/S0033291721001604

Matheson, B. E., Gorrell, S., Bohon, C., Agras, W. S., Le Grange, D., & Lock, J. (2020). Investigating early response to treatment in a multi-site study for adolescent bulimia nervosa. Frontiers in Psychiatry, 11, 92. https://doi.org/10.3389/fpsyt.2020.00092

Nagata, J. M., Bojorquez-Ramirez, P., Nguyen, A., Ganson, K. T., Machen, V. I., Cattle, C. J., Buckelew, S. M., & Garber, A. K. (2022). Sex differences in refeeding among hospitalized adolescents and young adults with eating disorders. The International journal of eating disorders, 55(2), 247–253. https://doi.org/10.1002/eat.23660

Radin, R. M., Epel, E. S., Daubenmier, J., Moran, P., Schleicher, S., Kristeller, J., Hecht, F. M., & Mason, A. E. (2020). Do stress eating or compulsive eating influence metabolic health in a mindfulness-based weight loss intervention? Health psychology: official journal of the Division of Health Psychology, American Psychological Association, 39(2), 147–158. https://doi.org/10.1037/hea0000807

Rienecke, R. D., Gorrell, S., Blalock, D. V., Smith, K., Lock, J., & Le Grange, D. (2021). Expressed emotion and long-term outcome among adolescents with anorexia nervosa. The International journal of eating disorders, 54(11), 2019–2024. https://doi.org/10.1002/eat.23613

Rienecke, R. D., Gorrell, S., Johnson, M., Duffy, A., Mehler, P. S., & Le Grange, D. (2023). Expressed emotion and treatment outcome in higher levels of care for eating disorders. The International journal of eating disorders, 56(3), 628–636. https://doi.org/10.1002/eat.23890

Van Huysse, J. L., Lock, J., Le Grange, D., & Rienecke, R. D. (2022). Weight gain and parental self-efficacy in a family-based partial hospitalization program. Journal of Eating Disorders, 10(1), 116. https://doi.org/10.1186/s40337-022-00634-6

Walker, D. C., Donahue, J. M., Heiss, S., Gorrell, S., Anderson, L. M., Brooks, J. M., Ehrlich, E. P., Morison, J. N., & Anderson, D. A. (2021). Rapid response is predictive of treatment outcomes in a transdiagnostic intensive outpatient eating disorder sample: A replication of prior research in a real-world setting. Eating and weight disorders, 26(5), 1345–1356. https://doi.org/10.1007/s40519-020-00939-y​

Novel or Innovative Treatments

Accurso, E. C., Cheng, J., Machen, V. I., Buckelew, S., Kreiter, A., Adams, S., Le Grange, D., Golden, N. H., & Garber, A. K. (2023). Hospital-based higher calorie refeeding and mealtime distress in adolescents and young adults with anorexia nervosa or atypical anorexia nervosa. The International journal of eating disorders, 56(6), 1219–1227. https://doi.org/10.1002/eat.23931

**Barney, A., Buckelew, S., Mesheriakova, V., & Raymond-Flesch, M. (2020). The COVID-19 pandemic and rapid implementation of adolescent and young adult telemedicine: Challenges and opportunities for innovation. The Journal of Adolescent Health, 67(2), 164–171. https://doi.org/10.1016/j.jadohealth.2020.05.006

**Bruett, L. D., Forsberg, S., Accurso, E. C., Gorrell, S., Hail, L., Keyser, J., Le Grange, D., & Huryk, K. M. (2022). Development of evidence-informed bridge programming to support an increased need for eating disorder services during the COVID-19 pandemic. Journal of Eating Disorders, 10, Article 71.

Brynes, N., Tarchichi, T., McCormick, A. A., & Downey, A. (2021). Restrictive eating disorders: Accelerating treatment outcomes in the medical hospital. Hospital Pediatrics, 11(7), 751–759. https://doi.org/10.1542/hpeds.2020-005389

Claudat, K., Reilly, E. E., Convertino, A. D., Trim, J., Cusack, A., & Kaye, W. H. (2022). Integrating evidence-based PTSD treatment into intensive eating disorders treatment: a preliminary investigation. Eating and Weight Disorders, 27(8), 3599–3607. https://doi.org/10.1007/s40519-022-01500-9

Downey, A. E., Boyd, M., Chaphekar, A. V., Woolley, J., & Raymond-Flesch, M. (2023). "But the reality is it's happening": A qualitative study of eating disorder providers about psilocybin-assisted psychotherapy. The International Journal of Eating Disorders, 56(11), 2142–2148. https://doi.org/10.1002/eat.24041

Gorrell, S., Vendlinski, S. S., Thompson, A. S., Downey, A. E., Kramer, R., Hail, L., Clifton, S., Forsberg, S., Reilly, E. E., Saunders, E., Buckelew, S. M., & Le Grange, D. (2023). Modification of an inpatient medical management protocol for pediatric Avoidant/Restrictive Food Intake Disorder: Improving the standard of care. Journal of Eating Disorders, 11(1), 165. https://doi.org/10.1186/s40337-023-00895-9

Hambleton, A., Le Grange, D., Miskovic-Wheatley, J., Touyz, S., Cunich, M., & Maguire, S. (2020). Translating evidence-based treatment for digital health delivery: A protocol for family-based treatment for anorexia nervosa using telemedicine. Journal of Eating Disorders, 8, 50. https://doi.org/10.1186/s40337-020-00328-x

Lock, J., Le Grange, D., Nicholls, D., & Couturier, J. (2021). Editorial: Innovations in Research and Practice of Family Based Treatment for Eating Disorders. Frontiers in Psychiatry, 11, 638503. https://doi.org/10.3389/fpsyt.2020.638503

Radin, R. M., Epel, E. S., Mason, A. E., Vaccaro, J., Fromer, E., Guan, J., & Prather, A. A. (2023). Impact of digital meditation on work stress and health outcomes among adults with overweight: A randomized controlled trial. PloS One, 18(3), e0280808. https://doi.org/10.1371/journal.pone.0280808

Stoody, V. B., Garber, A. K., Miller, C. A., & Bravender, T. (2023). Advancements in inpatient medical management of malnutrition in children and adolescents with restrictive eating disorders. The Journal of Pediatrics, 260, 113482. https://doi.org/10.1016/j.jpeds.2023.113482

Adapting Treatments for New Populations and/or Settings

Aarnio-Peterson, C. M., Le Grange, D., Mara, C. A., Modi, A. C., Offenbacker North, E., Zegarac, M., Stevens, K., Matthews, A., Mitan, L., & Shaffer, A. (2024). Emotion coaching skills as an augmentation to family-based therapy for adolescents with anorexia nervosa: A pilot effectiveness study with families with high expressed emotion. The International journal of eating disorders, 57(3), 682–694. https://doi.org/10.1002/eat.24149

**Accurso, E. C., Mu, K. J., Landsverk, J., & Guydish, J. (2021). Adaptation to family-based treatment for Medicaid-insured youth with anorexia nervosa in publicly-funded settings: Protocol for a mixed methods implementation scale-out pilot study. Journal of eating disorders, 9(1), 99. https://doi.org/10.1186/s40337-021-00454-0

Burton, C., Allan, E., Eckhardt, S., Le Grange, D., Ehrenreich-May, J., Singh, M., & Dimitropoulos, G. (2021). Case presentations combining family-based treatment with the unified protocols for transdiagnostic treatment of emotional disorders in children and adolescents for comorbid Avoidant Restrictive Food Intake Disorder and Autism Spectrum Disorder. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 30(4), 280–291.

**Dimitropoulos, G., Singh, M., Sauerwein, J., Pedram, P., Kimber, M., Pradel, M., Eckhardt, S., Forsberg, S., Keery, H., Allan, E., Bruett, L., & Le Grange, D. (2024). Examining clinicians' perceptions and experiences working with diverse families in family-based treatment: Common adaptations and considerations for treatment engagement. The International journal of eating disorders, 57(3), 635–647. https://doi.org/10.1002/eat.24144

**Goldschmidt, A. B., Tortolani, C. C., Accurso, E. C., Dunbar, E. P., Egbert, A. H., Donaldson, D., & Donaldson, A. A. (2023). Adapting family-based treatment for adolescent anorexia nervosa delivered in the home: A novel approach for improving access to care and generalizability of skill acquisition. Journal of eating disorders, 11(1), 130. https://doi.org/10.1186/s40337-023-00850-8

Haas, V., Kohn, M., Körner, T., Cuntz, U., Garber, A. K., Le Grange, D., Voderholzer, U., & Correll, C. U. (2021). Practice-based evidence and clinical guidance to support accelerated re-nutrition of patients with anorexia nervosa. Journal of the American Academy of Child and Adolescent Psychiatry, 60(5), 555–561. https://doi.org/10.1016/j.jaac.2020.09.010

Lebow, J., O'Brien, J. R. G., Mattke, A., Narr, C., Geske, J., Billings, M., Clark, M. M., Jacobson, R. M., Phelan, S., Le Grange, D., & Sim, L. (2021). A primary care modification of family-based treatment for adolescent restrictive eating disorders. Eating disorders, 29(4), 376–389. https://doi.org/10.1080/10640266.2019.1656468

Vendlinski, S. S., Laboe, A. A., Crest, P., McGinnis, C. G., Fennig, M., Wilfley, D. E., Taylor, C. B., Fitzsimmons-Craft, E. E., & Accurso, E. C. (2024). Adaptations of an online cognitive-behavioral therapy intervention for binge-purge type eating disorders in publicly-insured and uninsured adults: A pilot study. Research square, rs.3.rs-3879484. https://doi.org/10.21203/rs.3.rs-3879484/v1

How Does Treatment Work?

Berner, L. A., Reilly, E. E., Yu, X., Krueger, A., Trunko, M. E., Anderson, L. K., Chen, J., Simmons, A. N., & Kaye, W. H. (2022). Changes in cognitive and behavioral control after lamotrigine and intensive dialectical behavioral therapy for severe, multi-impulsive bulimia nervosa: an fMRI case study. Eating and weight disorders, 27(5), 1919–1928. https://doi.org/10.1007/s40519-021-01308-z

Reilly, E. E., Perry, T. R., Brown, T. A., Wierenga, C. E., & Kaye, W. H. (2021). Intolerance of uncertainty and eating disorder symptoms over the course of intensive treatment. Behavior therapy, 52(3), 698-708. https://doi.org/10.1016/j.beth.2020.09.002

Reilly, E. E., Wierenga, C. E., & Le Grange, D. (2024). Testing the role of associative learning in evidence-based treatments for anorexia nervosa. The International journal of eating disorders, 57(5), 1088–1095. https://doi.org/10.1002/eat.24161

Rienecke, R. D., & Le Grange, D. (2022). The five tenets of family-based treatment for adolescent eating disorders. Journal of Eating Disorders, 10(1), 60. https://doi.org/10.1186/s40337-022-00585-y